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Cardiovascular Parameters in a Swine Model of Normobaric Hypoxia Treated With 5-Hydroxymethyl-2-Furfural (5-HMF)
Conclusion: 5-HMF treatment decreased P50, improved SaO2, and mitigated increases in PAP in this swine model of NH. Introduction The reduction of barometric pressure at altitude is associated with reduced partial pressure of ambient Oxygen (PO2). With lower ambient PO2, it can be anticipated that alveolar (PAO2), arterial O2 (PaO2) and blood O2 content (CaO2) will decrease accordingly, resulting in a widely recognized decrease in maximal O2 consumption (VO2) (Dill and Adams, 1972; Lucas et al., 2011). In humans, with acute exposure to altitude, maximal VO2 decrements are measurable at elevations even as low as 580 ...
Source: Frontiers in Physiology - April 17, 2019 Category: Physiology Source Type: research

H1N1 (Swine Flu) Treatment Options for People...
What H1N1 (swine flu) treatment options are available for people with cancer? What medications are used for H1N1 (swine flu) treatment, when are they used, and what are the side effects?
Source: About.com Lung Cancer - January 12, 2014 Category: Cancer & Oncology Authors: lungcancer.guide at about.com Tags: health Source Type: news

Patient-based benefit-risk assessment of medicines: development, refinement, and validation of a content search strategy to retrieve relevant studies
J Med Libr Assoc. 2022 Apr 1;110(2):185-204. doi: 10.5195/jmla.2022.1306.ABSTRACTINTRODUCTION: Poor indexing and inconsistent use of terms and keywords may prevent efficient retrieval of studies on the patient-based benefit-risk assessment (BRA) of medicines. We aimed to develop and validate an objectively derived content search strategy containing generic search terms that can be adapted for any search for evidence on patient-based BRA of medicines for any therapeutic area.METHODS: We used a robust multistep process to develop and validate the content search strategy: (1) we developed a bank of search terms derived from s...
Source: J Med Libr Assoc AND... - April 20, 2022 Category: Databases & Libraries Authors: Hiba El Masri Treasure M McGuire Christine Dalais Mieke van Driel Helen Benham Samantha A Hollingworth Source Type: research